State Research Center of Virology and Biotechnology "Vector"

Three levels of anti-epidemic activities (AEA) are taken into account in modeling; these levels mainly determine the rate of detection and isolation (observation) of the infected persons, contacts, and suspects. These activities, as a rule, are imposed in a successive manner:
  1. Mild AEA1 imply isolation of the patients that visited a physician. This regime is used when there are unconfirmed suspicions about a possible outbreak onset, that is, when there are confirmed cases in other localities (regions), cases with evident disease signs have been recorded, and contact transmission routes have been detected with a characteristic incubation period; however, a laboratory confirmation is still absent. Contacts and suspects are not purposefully searched for;
  2. Moderate AEA2 imply quicker isolation of infected cases as well as detection and isolation (observation) of contacts and suspects. This regime is used in the case of confirmed suspicions on the onset of an outbreak but certain time period is required until all AEA are deployed; and
  3. Strict AEA3 imply even quicker isolation of infected cases as well as an active search for infected and contacts, including systematic door-to-door visits and, when necessary, quarantine.
In addition to these regimes, mass vaccination is applied for some infections with characteristic population and time coverage; vaccination of risk groups including contacts and suspects; and quarantine, with different degrees of activity reducing the infection rate.

For a number of infections in an epidemic (an outbreak) one of the countermeasures is the prophylactic administration of therapeutic drugs: immunomodulators, antibiotics, and so forth. The model itself does not provide such an intervention. However, it enables simulation of the intervention.